Young I M, Anderson D B, Plenderleith R W
Vet Rec. 1984 Oct 27;115(17):429-31. doi: 10.1136/vr.115.17.429.
Commercial dairy cows were given a routine injection of dinoprost tromethamine (prostaglandin F2 alpha THAM) in the early post partum period. The first service conception rate of 64 cows given a single 25 mg injection of dinoprost during the period 14 to 28 days after calving was 68 per cent, that of 64 untreated controls was 43 per cent. The difference was highly significant at the level P = 0.007. In cows with no blood progesterone and with basal progesterone concentrations at the time of treatment, indicating absence of an active corpus luteum, the mean conception rates for 30 treated and 38 control cows were 70 and 44 per cent, respectively, demonstrating that this is not a luteolytic effect. Although that implies a positive myometrial effect, the interval from calving to first service was not shortened in treated cows.
在产后早期，对商业奶牛进行了氯前列醇（前列腺素F2α三羟甲基氨基甲烷）的常规注射。在产犊后14至28天期间，对64头奶牛单次注射25毫克氯前列醇，其首次配种受胎率为68%，64头未处理的对照组奶牛的首次配种受胎率为43%。在P = 0.007水平上，差异高度显著。在治疗时无血孕酮且基础孕酮浓度表明无活性黄体的奶牛中，30头治疗奶牛和38头对照奶牛的平均受胎率分别为70%和44%，表明这不是溶黄体作用。虽然这意味着对子宫肌层有积极作用，但治疗奶牛从产犊到首次配种的间隔并未缩短。
