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[人子宫和输卵管雌二醇结合系统若干特性的比较特征]

[Comparative characteristics of several properties of the estradiol-binding system of the human uterus and fallopian tubes].

作者信息

Fanchenko N D

出版信息

Vopr Med Khim. 1984 Jul-Aug;30(4):116-8.

PMID:6506576
Abstract

Kinetic and thermodynamic parameters of estradiol-receptor interactions were studied in cytosol of human uterus endometrium and of uterus tubes. Specificity of these reactions was investigated. The receptor systems studied were distinctly dissimilar in the values of Ka equilibria, rate constants of association and dissociation with estradiol as well as in the affinity to a series of natural and synthetic estrogens.

摘要

在人子宫内膜和输卵管的胞质溶胶中研究了雌二醇-受体相互作用的动力学和热力学参数。研究了这些反应的特异性。所研究的受体系统在Ka平衡值、与雌二醇结合和解离的速率常数以及对一系列天然和合成雌激素的亲和力方面明显不同。

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