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[未经治疗及普萘洛尔治疗的下肢动脉循环障碍患者间歇治疗期间的血压及外周血流动力学表现]

[Behavior of blood pressure and peripheral hemodynamics in interval therapy in untreated and propranolol-treated patients with arterial circulatory disorders of the lower extremities].

作者信息

Winterfeld H J, Strangfeld D, Siewert H, Schmidt H H, Mederacke W

出版信息

Z Gesamte Inn Med. 1984 Sep 15;39(18):447-50.

PMID:6506819
Abstract

Searching for a possibility of an effective therapy of disturbances of peripheral arterial blood supply (stage I and II), the authors examined a medicamentously untreated group of patients as well as a comparable group of patients which was pretreated with propranolol. The two groups of patients performed twice a week an interval run exercise. Under the three-month training therapy in the two groups significant systolic and diastolic blood pressure reductions as well as statistically ascertained shortenings of the xenon-133-half-value time under working conditions and enlargements of the average functional vascular cross section A appeared. The distance of the intermittent claudication and the standardized moving up and down test prolonged. An influence on the microcirculation caused by propranolol could not be proved. The results are discussed on the basis of literature.

摘要

为探寻有效治疗外周动脉供血障碍(I期和II期)的可能性,作者对一组未经药物治疗的患者以及一组用普萘洛尔进行过预处理的可比患者组进行了检查。两组患者每周进行两次间歇跑步运动。在为期三个月的训练治疗中,两组患者的收缩压和舒张压均显著降低,且经统计学确定,工作状态下氙-133半衰期缩短,平均功能性血管横截面积A增大。间歇性跛行的距离以及标准化的上下移动测试时间延长。未证实普萘洛尔对微循环有影响。基于文献对结果进行了讨论。

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