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[脑循环功能不全早期表现患者不同睡眠阶段及周期的夜间睡眠与脑血流动力学]

[Nocturnal sleep and cerebral hemodynamics in different sleep stages and cycles among patients with early manifestations of cerebral circulatory insufficiency].

作者信息

Voloshin P V, Mertsalov V S, Ignatova N V

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(9):1316-21.

PMID:6506976
Abstract

Clinical and polygraphical (EEG, EOG, EMG, ECG, REG) studies of nocturnal sleep and of the hemodynamics were carried out in 60 patients with dyscirculatory encephalopathy induced by hypertension and atherosclerosis. The findings obtained demonstrate that the clinical picture in these patients is always characterized by sleep disturbances which decrease the level of their diurnal wakefulness and their capacity for work. Hemodynamic disturbances responsible for sleep disorders are in turn maintained by the latter which leads to the formation of the vicious circle. This is also supported by the fact that compromized cerebral circulation causes changes in the activity of the structures involved both in sleep-wakefulness function and the regulation of the cerebral and systemic hemodynamics. Hence, deviations in the nocturnal sleep pattern attended with pronounced alterations in the cerebral hemodynamics may contribute to the development of acute disorders of the cerebral circulation. The authors recommend correcting not only the disrupted structure of sleep but also the cerebral circulation with relation to he sleep-wakefulness cycle.

摘要

对60例由高血压和动脉粥样硬化引起的循环障碍性脑病患者进行了夜间睡眠和血液动力学的临床及多导记录(脑电图、眼电图、肌电图、心电图、视网膜电图)研究。所获结果表明,这些患者的临床症状总是以睡眠障碍为特征,而睡眠障碍会降低他们白天的清醒程度和工作能力。导致睡眠障碍的血液动力学紊乱反过来又由睡眠障碍维持,从而形成恶性循环。脑循环受损导致参与睡眠-觉醒功能以及脑和全身血液动力学调节的结构活动发生变化,这一事实也支持了上述观点。因此,夜间睡眠模式的偏差伴有脑血液动力学的明显改变,可能会促使脑循环急性障碍的发生。作者建议不仅要纠正睡眠结构紊乱,还要根据睡眠-觉醒周期纠正脑循环。

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