Man'kovskiĭ N B, Mints A Ia, Karaban' I N, Kuznetsova S M, Bachinskaia N Iu, Chuprovskaia N Iu
Vestn Akad Med Nauk SSSR. 1990(1):46-8.
Complex clinico-physiological examinations was performed in 300 patients of middle and old ages with early and pronounced dyscirculatory encephalopathy of atherosclerotic and, in most cases, hypertensive etiologies. The cerebral hemodynamics was found to be relatively independent of the central one in patients with early atherosclerotic encephalopathy; the level of the systemic circulation and that of the median regional cerebral flow were found to correlate in early and advanced hypertensive encephalopathy cases. The cerebral function was shown to be more associated with the cerebral flow in the early encephalopathy in elderly patients than in middle-aged ones. The individual and personal traits of the patients were largely related to the disease stage rather than to the predominant etiological factor.
对300例中老年患者进行了复杂的临床生理检查,这些患者患有早期和明显的循环障碍性脑病,病因多为动脉粥样硬化,且在大多数情况下为高血压。研究发现,早期动脉粥样硬化性脑病患者的脑血流动力学相对独立于中心血流动力学;在早期和晚期高血压性脑病病例中,全身循环水平与大脑中区域血流水平相关。研究表明,老年患者早期脑病时脑功能与脑血流的相关性比中年患者更强。患者的个体和个人特征在很大程度上与疾病阶段有关,而非主要病因。