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全膀胱切除术后膀胱癌的盆腔复发

[Pelvic recurrence of bladder carcinoma following total cystectomy].

作者信息

Takashi M, Murase T, Kato N, Shimoji T, Miyake K, Mitsuya H, Ichihara S

出版信息

Hinyokika Kiyo. 1984 Jul;30(7):913-7.

PMID:6507207
Abstract

The patients who undergo total cystectomy for high stage bladder carcinoma have poor prognosis because of local extension or distant metastases. In the case of recurrent lesions after total cystectomy, radiotherapy and chemotherapy are generally selected. In some cases of recurrent tumors localized within the pelvic cavity and with no distant metastases, however, surgical resection of the tumor is effective in local disease control combined with radio- and chemotherapy. Surgical treatment is not only effective in reducing the cell number in a bulky tumor, but also improves clinical symptoms and conditions such as pain, bleeding, rectal irritability, intestinal obstruction and so on. We present here three patients who underwent extensive operation for pelvic recurrence of bladder carcinoma following total cystectomy. Two of these cases died of progressive disease, nine months and five months after the extensive operations. The third patient died of acute pericarditis thirteen months after the second operation. Autopsy revealed that the surgical treatment was effective in controlling the local recurrence in the third case. Furthermore, some problems regarding pelvic recurrence and surgical treatment are discussed.

摘要

因局部浸润或远处转移而接受全膀胱切除术的晚期膀胱癌患者预后较差。对于全膀胱切除术后复发的病例,一般选择放疗和化疗。然而,在某些盆腔内局限性复发且无远处转移的肿瘤病例中,手术切除肿瘤联合放化疗对局部疾病控制有效。手术治疗不仅能有效减少巨大肿瘤中的细胞数量,还能改善疼痛、出血、直肠刺激、肠梗阻等临床症状和状况。我们在此介绍三例全膀胱切除术后因膀胱癌盆腔复发而接受广泛手术的患者。其中两例在广泛手术后九个月和五个月死于疾病进展。第三例患者在第二次手术后十三个月死于急性心包炎。尸检显示手术治疗对第三例患者的局部复发控制有效。此外,还讨论了有关盆腔复发和手术治疗的一些问题。

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