Loggan M, Moeller D D
Am J Gastroenterol. 1984 Dec;79(12):933-4.
Colonoscopy is an important diagnostic study in monitoring patients with chronic ulcerative colitis for carcinoma and dysplasia (precancer). A 76-year-old woman with chronic ulcerative colitis of 13 years' duration underwent colonoscopy. Biopsies were obtained at 10-cm intervals throughout the entire colon. A delayed perforation of the cecum was diagnosed 48 h after the diagnostic study. This necessitated a subtotal colectomy. It is suggested that in such patients cecal biopsies should be obtained with extreme caution because of the relative increase in intraluminal pressures and the relative thinness of the cecal wall.
结肠镜检查是监测慢性溃疡性结肠炎患者是否发生癌变和发育异常（癌前病变）的一项重要诊断性检查。一名患有13年慢性溃疡性结肠炎的76岁女性接受了结肠镜检查。在整个结肠每隔10厘米取活检组织。诊断性检查48小时后诊断出盲肠迟发性穿孔。这就需要进行次全结肠切除术。建议对于此类患者，由于肠腔内压力相对增加以及盲肠壁相对较薄，取盲肠活检时应格外谨慎。
