接受地塞米松治疗的精神科患者中，血浆地塞米松水平低与皮质醇水平升高之间的关联。
Association between low plasma levels of dexamethasone and elevated levels of cortisol in psychiatric patients given dexamethasone.
作者信息
Arana G W, Workman R J, Baldessarini R J
出版信息
Am J Psychiatry. 1984 Dec;141(12):1619-20. doi: 10.1176/ajp.141.12.1619.
PMID:6507668
Abstract
In psychiatric inpatients, positive results on 40 dexamethasone suppression tests (elevated cortisol levels) were strongly associated with low plasma levels of dexamethasone. Bioavailability or pharmacokinetic factors may contribute importantly to the outcome of the dexamethasone suppression test.
摘要
在精神科住院患者中，40次地塞米松抑制试验结果呈阳性（皮质醇水平升高）与血浆地塞米松水平低密切相关。生物利用度或药代动力学因素可能对地塞米松抑制试验的结果有重要影响。
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