Arabia M, Akutsu T
Ann Biomed Eng. 1984;12(1):29-48. doi: 10.1007/BF02410289.
A new test circulatory system (TCS) has been developed for the in vitro testing of artificial hearts (AH) and for research in cardiovascular engineering, when connected to an AH that mimics the natural heart. The TCS is controlled by five variables whereby the slopes of the systemic and pulmonary venous return curves and the mean circulatory pressure can be fixed. It allows us to observe the mutual influence between TCS and AH characteristics and particularly the blood volume distribution, the pressure distribution, and the flowrates in steady-state conditions and (in the near future) also in dynamic conditions. A steady-state mathematical analysis describing the TCS is reported. Numerical results for the human circulatory system at different levels of activity and in physiologic conditions are shown. A first prototype of the TCS has been working for more than one year. The experimental results are in agreement with the mathematical analysis.
一种新型测试循环系统（TCS）已被开发出来，用于人工心脏（AH）的体外测试以及心血管工程研究，它与模拟自然心脏的AH相连。TCS由五个变量控制，借此可以固定体循环和肺循环静脉回流曲线的斜率以及平均循环压力。它使我们能够观察TCS与AH特性之间的相互影响，特别是在稳态条件下（以及在不久的将来在动态条件下）的血容量分布、压力分布和流量。报告了描述TCS的稳态数学分析。展示了人体循环系统在不同活动水平和生理条件下的数值结果。TCS的首个原型已经运行了一年多。实验结果与数学分析一致。
