Ishizuka M
Gan To Kagaku Ryoho. 1984 Dec;11(12 Pt 2):2709-14.
Immunomodulatory and antitumor activities of the low molecular weight, microbially-derived immunomodulators, bestatin and forphenicinol are reviewed. In addition, the inhibitory effects of the antitumor antibiotics, aclacinomycin and oxanosine, on the generation of suppressor cells are also represented. It is suggested that these substances will be useful for cancer treatment by chemotherapy and/or immunotherapy.
综述了低分子量微生物来源的免疫调节剂贝他定和磷霉素氨丁三醇的免疫调节及抗肿瘤活性。此外,还介绍了抗肿瘤抗生素阿克拉霉素和奥沙诺星对抑制细胞生成的抑制作用。提示这些物质将有助于通过化疗和/或免疫疗法治疗癌症。