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[儿童肿瘤相关性高钙血症。20例]

[Hypercalcemia associated with tumors in children. 20 cases].

作者信息

Leblanc A, Hartmann O, Pons G, Caillaud J M, Couanet D, Lenoir G, Lemerle J

出版信息

Arch Fr Pediatr. 1984 Oct;41(8):551-5.

PMID:6508484
Abstract

Thirty episodes of hypercalcemia were observed in 20 children with solid tumors: principally 9 cases of non Hodgkin's lymphomas, 4 cases of rhabdomyosarcomas and 4 cases of Wilms' tumors. The 2 children with neurological manifestations and hypertension had the most severe symptoms secondary to the high calcium levels. However, hypercalcemia was asymptomatic in 8 of the 20 children. Focal seizures and metastatic calcifications subsequently occurred in 6 children. Emergency treatment of hypercalcemia often had partial or transient efficiency. In contrast, high calcium levels always returned to normal after anti-tumoral treatment.

摘要

在20名患有实体瘤的儿童中观察到30次高钙血症发作:主要为9例非霍奇金淋巴瘤、4例横纹肌肉瘤和4例威尔姆斯瘤。2名有神经学表现和高血压的儿童因高钙水平而出现最严重的症状。然而,20名儿童中有8名高钙血症无症状。随后,6名儿童出现局灶性癫痫发作和转移性钙化。高钙血症的紧急治疗通常只有部分或短暂的效果。相比之下,抗肿瘤治疗后高钙水平总是恢复正常。

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