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舱室分隔/气闸概念在飞机上的应用以及肺对快速减压的耐受性。

Application of the compartmentalization/airlock concept to aircraft and tolerance of lung to rapid decompression.

作者信息

Fang H S, Chang Y N

出版信息

Aviat Space Environ Med. 1984 Nov;55(11):1015-9.

PMID:6508681
Abstract

The incidence of pulmonary hemorrhage of different laboratory animals undergoing rapid decompression was found to be markedly decreased by applying the compartmentalization/airlock concept to simulated pressurized aircraft. It was observed that, in protected rabbit, mouse, and rat lungs, 6 of 24 (25%), 7 of 24 (29%), and 6 of 24 (25%), respectively, exhibited a few petechial hemorrhages following rapid decompression. In unprotected animals, however, all 72 lungs showed slight-to-very-severe degrees of decompression-induced hemorrhages. The percent of mortality of the unprotected animals undergoing rapid decompression was 47%, while there were no deaths in protected animals. The incidence of such pulmonary hemorrhages and the mortality of experimental animals indicate that compartmentalization, combined with an adequate airlock, would be of great value in protection against accidental decompression of pressurized aircraft.

摘要

通过将分隔/气闸概念应用于模拟加压飞机,发现不同实验动物在快速减压时肺出血的发生率显著降低。据观察,在受到保护的兔、小鼠和大鼠肺中,快速减压后分别有24只中的6只(25%)、24只中的7只(29%)和24只中的6只(25%)出现了少量瘀点性出血。然而,在未受保护的动物中,所有72只肺均出现了轻度至非常严重程度的减压诱导出血。快速减压的未受保护动物的死亡率为47%,而受保护动物没有死亡。此类肺出血的发生率和实验动物的死亡率表明,分隔与适当的气闸相结合,对于防止加压飞机意外减压具有重要价值。

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