Fang H S, Tsai M L, Lea I T
Aviat Space Environ Med. 1985 Dec;56(12):1209-12.
The effect of the application of the compartmentalization/airlock on accidental decompression was studied in conscious rats, mice, and guinea pigs. It was observed that in unprotected rats and mice, 78 of 102 middle ears (76.5%) exhibited hemorrhages with their eardrums intact; and in unprotected guinea pigs, 37 of 50 eardrums (74%) revealed rupture associated with hemorrhages of all middle ears (100%). Seven cases of malleus fractures (14%) were also found in unprotected guinea pigs. On the other hand, none of the protected animals showed signs of middle ear barotrauma. The protective effect on the tolerance of middle ears in the present study showed the same tendency as that on the tolerance of lungs in our previous study. These findings indicate that the application of the compartmentalization/airlock would be of great value in protection against accidental rapid decompression of pressurized aircraft and spacecraft.
在清醒的大鼠、小鼠和豚鼠身上研究了分隔/气闸应用对意外减压的影响。观察到，在未受保护的大鼠和小鼠中，102只中耳中有78只（76.5%）鼓膜完整但出现出血；在未受保护的豚鼠中，50只鼓膜中有37只（74%）显示破裂并伴有所有中耳出血（100%）。在未受保护的豚鼠中还发现7例锤骨骨折（14%）。另一方面，受保护的动物均未表现出中耳气压伤的迹象。本研究中对中耳耐受性的保护作用与我们先前研究中对肺耐受性的保护作用显示出相同的趋势。这些发现表明，分隔/气闸的应用在防止加压飞机和航天器意外快速减压方面具有重要价值。
