Zhuravlev A K, Murashko V V, Sherstnev M P, Antonova O V
Biull Eksp Biol Med. 1984 Nov;98(11):596-8.
Suspensions of red cells from normal subjects and cancer patients were incubated in the presence of hydrogen peroxide. The incubation gave rise to a flash of chemiluminescence including rapid and slow components. The concentration dependencies of chemiluminescence were plotted as was the dependence of chemiluminescence on the temperature of the suspension under test. The differences were found between chemiluminescence of donors' red cells and that of patients'. It is inferred that red cell membranes of cancer patients show both the decreased membrane resistance to the damage-inducing action of hydrogen peroxide and elevation of antioxidant activity.
将正常受试者和癌症患者的红细胞悬液在过氧化氢存在的情况下进行孵育。孵育过程中产生了一道化学发光闪光，包括快速和慢速成分。绘制了化学发光的浓度依赖性以及化学发光对受试悬液温度的依赖性。发现供体红细胞和患者红细胞的化学发光存在差异。据推断，癌症患者的红细胞膜对过氧化氢的损伤诱导作用的膜抗性降低，同时抗氧化活性升高。
