Milovanov A P, Mommadov A, Zelinskaia V V
Biull Eksp Biol Med. 1984 Nov;98(11):617-8.
Lung acinus components of 60 rats were studied by morphometry on the 2d, 4th and 6th week of stepped general cold exposure in a climatic chamber at a temperature of 5 degrees C to 20 degrees C. Stepped adaptation reorganization of the acinus of experimental rats was revealed, with this reorganization being in the form of an increase in the volume of the dead respiratory space, in the total alveolar surface, and hypervolemia of the capillary and arterial bed of the lungs. Dispersion analysis confirmed the agreement between the changes in the acinus and stages of cold exposure.
在气候舱中,于5摄氏度至20摄氏度的温度下,对60只大鼠进行逐步全身冷暴露,在第2周、第4周和第6周通过形态测量法研究肺腺泡成分。结果显示,实验大鼠的腺泡出现逐步适应性重构,表现为无效呼吸空间体积增加、肺泡总表面积增加以及肺毛细血管和动脉床血容量过多。离散分析证实了腺泡变化与冷暴露阶段之间的一致性。