Barrett A N, Summerbell D
Comput Biol Med. 1984;14(4):411-8. doi: 10.1016/0010-4825(84)90041-6.
This paper illustrates how a simple geometric model resembling the shape of the chick wing bud at an early growth stage can be mathematically expanded to simulate subsequent growth characteristics of the developing bud. The model was tested against several sets of experimental data and gave an acceptable representation of growth over the range considered. Representing growth patterns in this form enables the determination of differential growth characteristics in different parts of the bud and provides boundary constraints which will play an important part in the eventual evaluation of internal growth mechanisms.
本文阐述了一个类似于雏鸡翅芽早期生长阶段形状的简单几何模型如何能够在数学上进行扩展,以模拟发育中芽的后续生长特征。该模型针对几组实验数据进行了测试,并在所考虑的范围内给出了可接受的生长表示。以这种形式表示生长模式能够确定芽不同部位的差异生长特征,并提供边界约束,这将在最终评估内部生长机制中发挥重要作用。