Sarasso G, Aralda D, Makmur J, Campini R, Rossi P
G Ital Cardiol. 1984 Sep;14(9):655-62.
A multivariate step-wise analysis with death or heart failure as prognostic end-points was utilized in 62 patients with an acute myocardial infarction (AMI), to evaluate the age related short-term prognostic significance of selected M-Mode and two dimensional echocardiographic parameters, and to identify, among them, the best predictors of the clinical outcome. The echocardiographic examination was performed within 24 hours from the occurrence of cardiac chest pain. After a three months follow-up study, the patients were divided into groups: 9 patients who died (Group A), 53 patients who survived (Group B), subdivided into 41 asymptomatic patients (Group B1) and 12 patients with clinical signs of heart failure (Group B2). The selected parameters were: age, left ventricular end-diastolic and end-systolic diameters (LVEDD, LVESD), left atrial diameter (LAD), the electrocardiographic PR interval minus AC interval from the mitral echogram (PR-AC), the distance between the mitral E point and the septum (EPSS), total aortic excursion (TAE), and two dimensional wall motion score. From the step-wise analysis of groups A and B we classified the parameters as follows, the relative prognostic significance being highest on the left side: score greater than TAE greater than AGE greater than PR-AC greater than LVEDD (LAD, LVESD, EPSS). For groups B1 and B2 the following results were obtained: score greater than PR-AC greater than AGE greater than LVESD greater than EPSS (TAE, LVESD, LAD). In parenthesis are indicated the variables whose prognostic value did not reach any significant level. When a discriminant function was applied to the 5 most significant variables, we could identify 78% of the patients of group A, and 77% of those of the group B; of groups B1 and B2 we identified correctly 83% and 92% of the patients respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
对62例急性心肌梗死(AMI)患者进行了以死亡或心力衰竭为预后终点的多变量逐步分析,以评估所选M型和二维超声心动图参数与年龄相关的短期预后意义,并从中确定临床结局的最佳预测指标。超声心动图检查在心脏胸痛发作后24小时内进行。经过三个月的随访研究,患者被分为几组:9例死亡患者(A组),53例存活患者(B组),B组又分为41例无症状患者(B1组)和12例有心力衰竭临床体征的患者(B2组)。所选参数包括:年龄、左心室舒张末期和收缩末期直径(LVEDD、LVESD)、左心房直径(LAD)、心电图PR间期减去二尖瓣回声图的AC间期(PR-AC)、二尖瓣E点与室间隔的距离(EPSS)、主动脉总偏移(TAE)以及二维室壁运动评分。通过对A组和B组的逐步分析,我们将参数分类如下,相对预后意义从左到右依次降低:评分>TAE>年龄>PR-AC>LVEDD(LAD、LVESD、EPSS)。对于B1组和B2组,得到以下结果:评分>PR-AC>年龄>LVESD>EPSS(TAE、LVESD、LAD)。括号内为预后价值未达到任何显著水平的变量。当将判别函数应用于5个最显著变量时,我们能够正确识别出A组78%的患者以及B组77%的患者;对于B1组和B2组,分别正确识别出了83%和92%的患者。(摘要截断于250字)