Robertson W D, Nugent R A, Russell D B, Singer-Jordan J, Graeb D A, Lapointe J S, Morris D C
Invest Radiol. 1984 Nov-Dec;19(6 Suppl):S308-11. doi: 10.1097/00004424-198411001-00006.
Sixty patients from the University of British Columbia, Vancouver General Hospital, and University of Alberta Hospitals Edmonton participated in an open-labelled clinical study on the safety, tolerability and efficacy of ioxaglic acid (Hexabrix) in cerebral angiography. Only 4% of patients experienced significant pain during carotid and brachiocephalic injections of Hexabrix. No increased incidence of side effects or adverse effects were encountered. In addition, radiographic film quality overall was excellent and comparable to that obtained using conventional contrast agents. Hexabrix is a safe and effective contrast agent for cerebral angiography.
来自温哥华英属哥伦比亚大学、温哥华总医院以及埃德蒙顿阿尔伯塔大学医院的60名患者参与了一项关于碘克沙酸（Hexabrix）在脑血管造影术中安全性、耐受性及有效性的开放标签临床研究。在使用Hexabrix进行颈动脉和头臂血管注射时，仅有4%的患者经历了明显疼痛。未发现副作用或不良反应的发生率增加。此外，造影胶片的整体质量极佳，与使用传统造影剂时获得的质量相当。Hexabrix是一种用于脑血管造影的安全有效的造影剂。
