Risco C A, Reynolds J P, Hird D
J Am Vet Med Assoc. 1984 Dec 15;185(12):1517-9.
Blood samples were collected from 53 dairy cows with uterine prolapse and from 53 cows with normal parturition (no uterine prolapse) matched by dairy as controls for various management programs among dairies. Cows with uterine prolapse had significantly lower total serum calcium content than did controls (P less than 0.01). Mean (+/- SEM) serum calcium content (mg/dl) for affected cows and controls were 6.08 (+/- 0.25) and 6.96 (+/- 0.20), respectively. Severe hypocalcemia (less than 4 mg/dl) was found in 10 (19%) of the affected cows, compared with 1 (1.8%) of the controls. Fifteen (28%) of the affected cows had moderate hypocalcemia (4.1 to 6.0 mg/dl), compared with 14 (26%) of the controls; 19 (36%) of the affected cows were mildly hypocalcemic (6.1 to 7.9 mg/dl), compared with 25 (47%) of the controls. Nine (17%) of the affected cows and 13 (25%) of the controls were within the normal range of calcium content (greater than 8 mg/dl). Nine of the affected cows were first-calf cows. The serum of these animals did not have significantly lower calcium concentrations, compared with controls matched by parity. Serum calcium values (mg/dl) for 9 first-calf cows and the 9 matched controls were 7.24 (+/- 0.42) and 7.00 (+/- 0.39), respectively. It was concluded that hypocalcemia was associated with uterine prolapse in multiparous dairy cows and, along with other factors, is involved as an etiologic factor for this puerperal condition.
从53头患有子宫脱垂的奶牛以及53头正常分娩（无子宫脱垂）的奶牛中采集血样，这些奶牛按奶牛场进行匹配，作为各奶牛场不同管理方案的对照。患有子宫脱垂的奶牛血清总钙含量显著低于对照组（P小于0.01）。患病奶牛和对照组的平均（±标准误）血清钙含量（mg/dl）分别为6.08（±0.25）和6.96（±0.20）。10头（19%）患病奶牛出现严重低钙血症（低于4mg/dl），而对照组为1头（1.8%）。15头（28%）患病奶牛出现中度低钙血症（4.1至6.0mg/dl），对照组为14头（26%）；19头（36%）患病奶牛轻度低钙血症（6.1至7.9mg/dl），对照组为25头（47%）。9头（17%）患病奶牛和13头（25%）对照组奶牛的钙含量在正常范围内（大于8mg/dl）。9头患病奶牛为初产奶牛。与按胎次匹配的对照组相比，这些动物的血清钙浓度没有显著降低。9头初产奶牛和9头匹配对照组的血清钙值（mg/dl）分别为7.24（±0.42）和7.00（±0.39）。得出的结论是，低钙血症与经产奶牛的子宫脱垂有关，并且与其他因素一起，是这种产后疾病的病因之一。
