头颈部大手术中的化学预防
Chemoprophylaxis in major head and neck surgery.
作者信息
Raine C H, Bartzokas C A, Stell P M, Gallway A, Corkill J E
出版信息
J R Soc Med. 1984 Dec;77(12):1006-9. doi: 10.1177/014107688407701204.
Abstract
Wound infections are a significant complication following major oncological head and neck surgery. In view of the controversy surrounding the use of chemoprophylaxis a controlled trial was designed. Intravenous Augmentin (amoxycillin and clavulanic acid) was shown to reduce significantly (P less than 0.025) the incidence of postoperative sepsis.
摘要
伤口感染是大型头颈部肿瘤手术后的一个严重并发症。鉴于在化学预防药物使用方面存在的争议，设计了一项对照试验。结果显示，静脉注射安灭菌（阿莫西林和克拉维酸）可显著降低（P<0.025）术后脓毒症的发生率。
相似文献
1
Chemoprophylaxis in major head and neck surgery.头颈部大手术中的化学预防
J R Soc Med. 1984 Dec;77(12):1006-9. doi: 10.1177/014107688407701204.
2
Amoxycillin-clavulanic acid (Augmentin) versus metronidazole as prophylaxis in hysterectomy: a prospective, randomized clinical trial.阿莫西林-克拉维酸（奥格门汀）与甲硝唑在子宫切除术中的预防性应用：一项前瞻性随机临床试验。
Br J Obstet Gynaecol. 1988 Mar;95(3):286-93. doi: 10.1111/j.1471-0528.1988.tb06871.x.
3
Amoxycillin-clavulanic acid (Augmentin) versus metronidazole as prophylaxis in hysterectomy: a prospective randomized clinical trial.阿莫西林-克拉维酸（奥格门汀）与甲硝唑在子宫切除术中作为预防用药的比较：一项前瞻性随机临床试验。
Br J Obstet Gynaecol. 1988 Sep;95(9):951. doi: 10.1111/j.1471-0528.1988.tb06589.x.
4
Amoxycillin-clavulanic acid (Augmentin) antibiotic prophylaxis against wound infections in renal failure patients.
J Antimicrob Chemother. 1988 Sep;22(3):363-9. doi: 10.1093/jac/22.3.363.
5
[A combination of amoxycillin with clavulanic acid (Augmentin) in various types of urinary tract infections caused by microbes producing beta-lactamase].
Cas Lek Cesk. 1985 Jun 7;124(23):711-4.
6
Augmentin (Amoxycillin and clavulanic acid) in the treatment of urinary tract infections and skin and soft tissue infections.
Singapore Med J. 1983 Oct;24(5):299-302.
7
Preincisional intraparietal Augmentin in abdominal operations.腹部手术中术前腹腔内使用阿莫西林克拉维酸钾。
Ann R Coll Surg Engl. 1989 Mar;71(2):97-100.
8
Augmentin (amoxycillin-clavulanic acid) compared with co-trimoxazole in urinary tract infections.阿莫西林克拉维酸（奥格门汀）与复方新诺明治疗尿路感染的比较
Br Med J (Clin Res Ed). 1984 Jul 14;289(6437):82-3. doi: 10.1136/bmj.289.6437.82.
9
Prospective, randomized study comparing amoxycillin-clavulanic acid and cefamandole for the prevention of wound infection in high-risk patients undergoing elective biliary surgery.
J Hosp Infect. 1992 Nov;22 Suppl A:33-41. doi: 10.1016/s0195-6701(05)80005-2.
10
Metronidazole and Augmentin in the prevention of sepsis after appendicectomy.
Br J Surg. 1985 Jul;72(7):571-3. doi: 10.1002/bjs.1800720724.
引用本文的文献
1
Effect of Clindamycin compared with Ampicillin-Sulbactam as prophylactic antibiotics for wound infections following major surgery for head and neck cancer: A meta-analysis.克林霉素与氨苄西林-舒巴坦预防头颈部恶性肿瘤根治术后切口感染的效果比较：Meta 分析。
Int Wound J. 2023 Dec;20(10):4151-4158. doi: 10.1111/iwj.14312. Epub 2023 Jul 22.
2
Perioperative Topical Antisepsis and Surgical Site Infection in Patients Undergoing Upper Aerodigestive Tract Reconstruction.上消化道重建患者的围手术期局部抗菌和手术部位感染。
JAMA Otolaryngol Head Neck Surg. 2022 Jun 1;148(6):547-554. doi: 10.1001/jamaoto.2022.0684.
3
Perioperative Antibiotics in Clean-Contaminated Head and Neck Surgery: A Systematic Review and Meta-Analysis.头颈部清洁-污染手术围手术期抗生素应用：系统评价和荟萃分析。
Adv Ther. 2020 Apr;37(4):1360-1380. doi: 10.1007/s12325-020-01269-2. Epub 2020 Mar 5.
4
Quality Assessment in Supportive Care in Head and Neck Cancer.头颈部癌症支持性护理中的质量评估
Front Oncol. 2019 Sep 18;9:926. doi: 10.3389/fonc.2019.00926. eCollection 2019.
5
Antimicrobial prophylaxis for major head and neck surgery in cancer patients.癌症患者头颈部大手术的抗菌预防
Antimicrob Agents Chemother. 1988 Oct;32(10):1557-9. doi: 10.1128/AAC.32.10.1557.
6
Amoxicillin/clavulanic acid. An update of its antibacterial activity, pharmacokinetic properties and therapeutic use.阿莫西林/克拉维酸：抗菌活性、药代动力学特性及治疗用途的最新进展
Drugs. 1990 Feb;39(2):264-307. doi: 10.2165/00003495-199039020-00008.
本文引用的文献
1
The role of prophylactic antibiotic therapy in control of staphylococcal infections following cancer surgery.预防性抗生素治疗在控制癌症手术后葡萄球菌感染中的作用。
Surg Gynecol Obstet. 1962 Mar;114:345-52.
2
WOUND SEPSIS AFTER CLEAN OPERATIONS.清洁手术后的伤口脓毒症
Lancet. 1964 May 16;1(7342):1095-7. doi: 10.1016/s0140-6736(64)91291-7.
3
Wound infection in otolaryngologic surgery and the inexpediency of antibiotic prophylaxis.耳鼻喉科手术中的伤口感染及抗生素预防的不合理性。
Laryngoscope. 1963 Feb;73:165-84. doi: 10.1288/00005537-196302000-00003.
4
The case against antibiotic prophylaxis in major head and neck surgery.反对在重大头颈外科手术中使用抗生素预防的案例。
Laryngoscope. 1961 Jun;71:647-53. doi: 10.1002/lary.5540710606.
5
The role of metronidazole in the prevention of fistulae following total laryngectomy.甲硝唑在全喉切除术后预防瘘管形成中的作用。
Clin Oncol. 1980 Mar;6(1):71-7.
6
Comparative studies of two systems of prophylactic antibiotics in head and neck surgery.头颈部手术中两种预防性抗生素系统的比较研究。
Clin Otolaryngol Allied Sci. 1981 Jun;6(3):159-64. doi: 10.1111/j.1365-2273.1981.tb01526.x.
7
Antibiotic prophylaxis in surgery.手术中的抗生素预防
Clin Otolaryngol Allied Sci. 1981 Jun;6(3):157-8. doi: 10.1111/j.1365-2273.1981.tb01525.x.
8
Antibiotic prophylaxis in surgery for head and neck cancer. Comparative study of short and prolonged administration of carbenicillin.
J Antimicrob Chemother. 1981 Jun;7(6):665-71. doi: 10.1093/jac/7.6.665.
9
Chemoprophylaxis for surgery of the head and neck.
Ann Otol Rhinol Laryngol Suppl. 1981 May-Jun;90(3 Pt 3):8-12. doi: 10.1177/00034894810903s204.
10
Bacteriological assessment of patients undergoing major head and neck surgery.接受头颈大手术患者的细菌学评估。
Clin Otolaryngol Allied Sci. 1984 Apr;9(2):99-103. doi: 10.1111/j.1365-2273.1984.tb01480.x.
Zotero 插件