头颈部大手术中的化学预防
Chemoprophylaxis in major head and neck surgery.
作者信息
Raine C H, Bartzokas C A, Stell P M, Gallway A, Corkill J E
出版信息
J R Soc Med. 1984 Dec;77(12):1006-9. doi: 10.1177/014107688407701204.
Abstract
Wound infections are a significant complication following major oncological head and neck surgery. In view of the controversy surrounding the use of chemoprophylaxis a controlled trial was designed. Intravenous Augmentin (amoxycillin and clavulanic acid) was shown to reduce significantly (P less than 0.025) the incidence of postoperative sepsis.
摘要
伤口感染是大型头颈部肿瘤手术后的一个严重并发症。鉴于在化学预防药物使用方面存在的争议，设计了一项对照试验。结果显示，静脉注射安灭菌（阿莫西林和克拉维酸）可显著降低（P<0.025）术后脓毒症的发生率。
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