Karlsson S, Griffiths B, Swallow D M, Hopkinson D A, Wallis P G
J Med Genet. 1984 Dec;21(6):441-6. doi: 10.1136/jmg.21.6.441.
Ten lectins have been used to detect glycoproteins, after SDS polyacrylamide gel electrophoresis and gel isoelectric focusing, in fibroblasts, red cell membranes, urine, and plasma of patients and obligate heterozygotes with cystic fibrosis. No disease specific changes were detected but considerable individual variation was observed, some of which was attributed to known genetic polymorphisms unrelated to cystic fibrosis.
在对囊性纤维化患者及 obligate 杂合子的成纤维细胞、红细胞膜、尿液和血浆进行十二烷基硫酸钠聚丙烯酰胺凝胶电泳和凝胶等电聚焦后，使用了十种凝集素来检测糖蛋白。未检测到疾病特异性变化，但观察到相当大的个体差异，其中一些归因于与囊性纤维化无关的已知基因多态性。
