Tsukiyama I, Kakehi M, Yanagawa S, Watai K, Ono R, Watanabe S, Kitagawa T
Gan No Rinsho. 1984 Oct;30(13):1693-9.
A case of an extra-abdominal desmoid tumor in a 17-year-old female is reported. At the time of the first examination, the tumor was found to already involve the floor of the mouth, the submandibular region, both sides of the neck, the anterior chest wall and the mediastinum and hence was considered inoperable. The patient was treated by external irradiation and interstitial irradiation (Ir and Au). The therapeutic response was very slow, becoming noticeable 4 months after completion of the therapy and lasting for more than a year. Experience in this case indicates that in order for radiotherapy to prove successful in the treatment of desmoid tumor, it must be administered in relatively high doses. Since desmoid tumors reportedly have the potential for sarcomatous transformation, a long-term follow-up seems to be necessary in the management of patients with this neoplasm. It is considered that inoperable extra-abdominal desmoid tumors are a good indication for radiation therapy.
报告了一例17岁女性的腹外硬纤维瘤病例。首次检查时，发现肿瘤已累及口腔底部、下颌下区域、颈部两侧、前胸壁和纵隔，因此被认为无法手术切除。该患者接受了外照射和组织间照射（铱和金）治疗。治疗反应非常缓慢，在治疗结束4个月后才变得明显，并持续了一年多。该病例的经验表明，为使放疗成功治疗硬纤维瘤，必须给予相对高的剂量。据报道，由于硬纤维瘤有肉瘤样变的可能，因此对该肿瘤患者的管理似乎有必要进行长期随访。认为无法手术切除的腹外硬纤维瘤是放射治疗的良好适应证。
