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[放线菌酮和放线菌素D对日本小克银汉霉磷脂和中性脂质含量的影响]

[Effect of cycloheximide and actinomycin D on the phospholipid and neutral lipid content of Cunninghamella japonica].

作者信息

Mikhaĭlova M V, Feofilova E P, Rozantsev E G, Arkhipova G V, Shirokova E A

出版信息

Mikrobiologiia. 1984 Sep-Oct;53(5):816-21.

PMID:6513820
Abstract

Changes in the composition of neutral lipids and phospholipids were studied during the growth of Cunninghamella japonica under the action of cycloheximide and actinomycin D. The data were used to discuss how the synthesis of enzymes catalysing the formation of individual lipid classes was regulated and whether it would be possible to control the composition of phospholipids and neutral lipids using inhibitors of RNA and protein synthesis. The results are also indicative of a certain correlation between growth phases of the fungus and changes in certain characteristics of membrane lipids.

摘要

在环己酰亚胺和放线菌素D作用下,研究了日本小克银汉霉生长过程中中性脂质和磷脂组成的变化。利用这些数据讨论了催化各个脂质类别形成的酶的合成是如何调控的,以及是否有可能使用RNA和蛋白质合成抑制剂来控制磷脂和中性脂质的组成。结果还表明真菌的生长阶段与膜脂某些特性的变化之间存在一定的相关性。

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