Koletzko S, Ritzl F, Wendel U, Koletzko B, Lombeck I, Bremer H J
Monatsschr Kinderheilkd. 1984 Oct;132(10):791-6.
Scintigraphy with 131I-m-BG was used in 4 children with a history of multiple pheochromocytomas in order to localize further catecholamine-producing tumors prior to surgery. We overlook 7 scintigraphies without any side effect. Phenoxybenzamine did not interfere with tracer uptake into tumors. Scintigraphic localization of even smallest extra-adrenal tumors was successful in all cases. In most cases we were dealing with benign pheochromocytomas, but also a ganglioneuroma and metastases of a malignant pheochromocytoma could be revealed. Scintigraphy is a reliable technique for tracing pheochromocytomas and catecholamine-producing ganglioneuromas. It seems to be superior to other non-invasive techniques, furthermore, invasive techniques bearing higher risks may be suspended.
对4例有多发嗜铬细胞瘤病史的儿童采用¹³¹I-间位碘苄胍闪烁扫描法，以便在手术前进一步定位产生儿茶酚胺的肿瘤。我们进行了7次闪烁扫描，未出现任何副作用。酚苄明不影响示踪剂在肿瘤中的摄取。在所有病例中，即使是最小的肾上腺外肿瘤的闪烁扫描定位均获成功。大多数病例为良性嗜铬细胞瘤，但也发现了1例神经节瘤和1例恶性嗜铬细胞瘤转移灶。闪烁扫描是追踪嗜铬细胞瘤和产生儿茶酚胺的神经节瘤的可靠技术。它似乎优于其他非侵入性技术，此外，可避免采用有较高风险的侵入性技术。
