Nedzelski J M, Iazzetta J J
Otolaryngol Clin North Am. 1984 Nov;17(4):803-9.
We believe that in many instances the clinical indications for steroid administration are at best marginal, the results indeterminate. Fortunately, most such treatments are short and consequently the risk of serious side effects is minimal. A systematic effort to evaluate effects of corticosteroids in statistically significant groups of patients with otolaryngologic disorders continues to be a necessity. This observation made by Lederer et al. 15 years ago continues to be valid today.
我们认为,在许多情况下,使用类固醇的临床指征充其量只是处于边缘状态,结果也不确定。幸运的是,大多数此类治疗时间较短,因此严重副作用的风险极小。有必要对患有耳鼻喉科疾病的患者进行统计学意义上的分组,以系统地评估皮质类固醇的效果。15年前莱德勒等人的这一观察结果如今仍然有效。