Skoutakis V A, Acchiardo S R, Wojciechowski N J, Carter C A
Pharmacotherapy. 1984 Nov-Dec;4(6):392-7. doi: 10.1002/j.1875-9114.1984.tb03402.x.
Studies have suggested that microencapsulated preparations of potassium chloride may pose less risk to the upper gastrointestinal mucosa than the currently available wax-matrix preparations. Based on our own clinical experience and data available from the literature, we have concluded that (1) liquid and slow-release preparations of potassium chloride are safe and effective when used appropriately and (2) at present there is no conclusive evidence to suggest that lesions of the upper gastrointestinal tract are more prevalent with one slow-release preparation than with another.
研究表明，与目前可用的蜡基质制剂相比，微囊化氯化钾制剂对上消化道黏膜造成的风险可能更小。基于我们自己的临床经验和文献中的现有数据，我们得出结论：（1）氯化钾的液体和缓释制剂在适当使用时是安全有效的；（2）目前没有确凿证据表明一种缓释制剂比另一种更易导致上消化道病变。
