Lee T M, Moltz H
Physiol Behav. 1984 Sep;33(3):391-5. doi: 10.1016/0031-9384(84)90159-8.
We examined the lipid composition of blood and myelin in preweanling rats denied access to maternal feces. Levels of triglycerides and free fatty acids in the blood were reduced and in the brain the amount of myelin and the phospholipid concentration in myelin were also reduced. The addition of deoxycholic acid to ordinary laboratory chow prevented these deficiencies. We conclude that response to the maternal pheromone and the subsequent ingestion of deoxycholic acid through maternal feces promotes the deposition of normal brain myelin.
我们研究了无法接触母体粪便的断奶前大鼠血液和髓磷脂的脂质组成。血液中甘油三酯和游离脂肪酸水平降低，大脑中髓磷脂的量以及髓磷脂中的磷脂浓度也降低。在普通实验室饲料中添加脱氧胆酸可预防这些缺乏症。我们得出结论，对母体信息素的反应以及随后通过母体粪便摄入脱氧胆酸可促进正常脑髓磷脂的沉积。
