Eitschberger E, Gammert C, Masing H, Pesch H J
Laryngol Rhinol Otol (Stuttg). 1978 May;57(5):440-4.
A histological study is presented on 18 cartilage grafts, conserved in Merthiolat TM, which had been implanted for reconstruction of the caudal border of the nose for time periods of 1 month up to 11 years. These cartilage graft preparations were compared to non graft cartilage from patients died in an age of 37, 51 and 53 years respectively. Our findings show that cartilage grafts are eroded from the edge by resorption granulations of the host. Besides resorption one case showed purulent chondritis and another one osteoneogenesis. The extent of the erosion and the resorption rate seem to depend strongly on the original quality of the cartilage graft. This is possibly due to degenerative focuses which could be found in all of the natural cartilage preparations. After our opinion these focuses regarded like "loci minoris resistentiae". Therefore cartilage material to be used for rhinoplasty ought to be checked for such degenerative focuses.
本文对18块保存在硫柳汞中的软骨移植物进行了组织学研究，这些移植物已被植入用于鼻尾缘重建，植入时间从1个月到11年不等。将这些软骨移植物制剂与分别死于37岁、51岁和53岁患者的非移植软骨进行比较。我们的研究结果表明，软骨移植物会被宿主的吸收肉芽从边缘侵蚀。除了吸收外，1例显示脓性软骨炎，另1例显示骨生成。侵蚀程度和吸收率似乎很大程度上取决于软骨移植物的原始质量。这可能是由于在所有天然软骨制剂中都能发现的退行性病灶。我们认为这些病灶就像“抵抗力较弱的部位”。因此，用于隆鼻的软骨材料应该检查是否存在这种退行性病灶。
