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[肾切除术对恶性肾性高血压的降压作用及后期随访中残余肾脏的功能]

[Hypotensive effect of nephrectomy in malignant renal hypertension and the function of the remaining kidney at late follow-up].

作者信息

Rustamova M T, Iunusov R A

出版信息

Ter Arkh. 1984;56(9):37-40.

PMID:6515545
Abstract

The long-term results of nephrectomy were evaluated in 27 patients with malignant renal hypertension. The hypotensive effect of nephrectomy, function of the remaining kidney, central hemodynamics, and peripheral blood renin were investigated. It was found that hypertension remitted in subjects with an unaffected remaining kidney which completely compensated for the function of the removed kidney and maintained blood pressure within normal. Nephrectomy performed during malignant arterial hypertension that developed because of unilateral pyelonephritis and unilateral stenosing of the renal artery with a sufficient total renal function before surgery led to a prolonged remission of arterial hypertension and reverse development of the symptoms of its malignancy. Hypertension did not remit during chronic pyelonephritis of a single kidney. Renal function was substantially decreased as compared with the control group.

摘要

对27例恶性肾性高血压患者肾切除术的长期结果进行了评估。研究了肾切除术的降压效果、剩余肾脏的功能、中心血流动力学和外周血肾素。结果发现,剩余肾脏未受影响且能完全代偿切除肾脏功能并将血压维持在正常范围内的患者,高血压得以缓解。因单侧肾盂肾炎和单侧肾动脉狭窄导致的恶性动脉高血压患者,术前总肾功能充足,行肾切除术后可使动脉高血压长期缓解,其恶性症状逆向发展。单侧肾脏慢性肾盂肾炎患者高血压未缓解。与对照组相比,肾功能显著下降。

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1
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Ter Arkh. 1984;56(9):37-40.
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