国际细胞交换十年进展报告

Ten-year progress report of the International Cell Exchange.

作者信息

Loon J, Takemura S, Terasaki P I

出版信息

Tissue Antigens. 1984 Oct;24(4):215-27. doi: 10.1111/j.1399-0039.1984.tb02130.x.

DOI:10.1111/j.1399-0039.1984.tb02130.x

Abstract

For the past 10 years, the International Cell Exchange has been a useful tool for testing rare and unusual HLA antigens and monitoring the progress in detection of recognized specificities. Of special interest are the antigens proposed in the 8th Workshop - 8w57, 8w58, 8w59, and 8w66. Marked improvement could be seen in the detection of 8w59 (29%) and 8w66 (31%). Possible new variants of the A9 and A10 complexes were tested in several exchanges. As shown by the increasing yearly average percentages of detection, laboratories are improving in their ability to type Aw23, Aw24, A25, A26, A29; Bw39, Bw41, Bw54, Bw55, Bw57, Bw58, Bw60 and Bw62. Over 90% of the laboratories are now able to detect Aw24; B5, B17, and B40, and A29 has attained the status of being well defined.

摘要

在过去十年中，国际细胞交换一直是检测罕见和特殊HLA抗原以及监测公认特异性检测进展的有用工具。特别令人感兴趣的是第八届研讨会提出的抗原——8w57、8w58、8w59和8w66。在8w59（29%）和8w66（31%）的检测中可以看到显著改善。在几次交换中对A9和A10复合物可能的新变体进行了检测。从逐年增加的平均检测百分比可以看出，各实验室在对Aw23、Aw24、A25、A26、A29；Bw39、Bw41、Bw54、Bw55、Bw57、Bw58、Bw60和Bw62进行分型的能力方面正在提高。现在超过90%的实验室能够检测出Aw24；B5、B17和B40，并且A29已达到明确定义的状态。