Krosse B, Neumann G, Graff J, Trenckmann H
Z Gesamte Inn Med. 1984 Oct 1;39(19):469-73.
In 102 patients with typical symptoms of angina pectoris who underwent a coronary angiography a Dipyridamol test was performed. The result was a sensitivity of about 84% concerning the coronary heart disease and a specifity of about 93%. In the same test persons the ECG after work showed a sensitivity of about 84% and a specifity of about 57%. Dipyridamol test and bicycle ergometry are methods of the same value for the preinvasive diagnostics of the coronary heart disease which should supplement each other. The higher specifity of the ECG changes in the Dipyridamol test was evident in comparison to the bicycle ergometry. In 85 of our patients the Tl-201-scintigraphy was carried out under Dipyridamol and ergometer stress. For the Tl-201-scintigraphy under Dipyridamol a sensitivity of about 70% and a specifity of about 81,5% was the result. In the Tl-201-scintigraphy under ergometer load a sensitity ob about 84% and a specifity of about 57% was the result. The proportion of exactly positive findings increased with the number of the stenosed vessels under ergometer as well as Dipyridamol intervention. A negative load scintigraphy does not exclude a coronary heart disease, but renders a three-vessel-disease very improbable.
对102例有典型心绞痛症状且接受了冠状动脉造影的患者进行了双嘧达莫试验。结果显示，该试验对冠心病的敏感性约为84%，特异性约为93%。在相同受试人群中，运动后心电图的敏感性约为84%，特异性约为57%。双嘧达莫试验和自行车测力计测试对于冠心病的无创诊断具有同等价值，二者应相互补充。与自行车测力计测试相比，双嘧达莫试验中心电图改变的特异性更高。在我们的85例患者中，在双嘧达莫和测力计负荷下进行了铊-201闪烁扫描。双嘧达莫负荷下铊-201闪烁扫描的结果是敏感性约为70%，特异性约为81.5%。测力计负荷下铊-201闪烁扫描的结果是敏感性约为84%，特异性约为57%。在测力计以及双嘧达莫干预下，确切阳性结果的比例随狭窄血管数量的增加而增加。负荷闪烁扫描阴性不能排除冠心病，但可使三支血管病变的可能性非常小。
