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[氯美噻唑中毒]

[Clomethiazole poisoning].

作者信息

Klug E, Schneider V

出版信息

Z Rechtsmed. 1984;93(2):89-94. doi: 10.1007/BF00200767.

DOI:10.1007/BF00200767
PMID:6516604
Abstract

Clomethiazol can cause addiction, it can cause misbehavior in street traffic, and overdosage can lead to death. This paper presents 18 fatal cases in which clomethiazol played an essential role. This type of intoxication can be indicated by case history, easily identifiable tablets in the stomach contents, and a characterized odor. Since clomethiazol is easy to overlook during the general chemical analysis, a special gas chromatographical investigation should be made.

摘要

氯美噻唑可导致成瘾,可引起街头交通中的不当行为,过量服用可导致死亡。本文介绍了18例氯美噻唑起关键作用的致命病例。这种中毒情况可通过病史、胃内容物中易于识别的药片以及特征性气味来表明。由于在一般化学分析中氯美噻唑容易被忽视,因此应进行特殊的气相色谱研究。

相似文献

1
[Clomethiazole poisoning].[氯美噻唑中毒]
Z Rechtsmed. 1984;93(2):89-94. doi: 10.1007/BF00200767.
2
[On the detection of clomethiazole in urine (author's transl)].
Z Rechtsmed. 1978 Sep 28;82(1):37-41. doi: 10.1007/BF02114499.
3
Analysis of chlormethiazole, ethchlorvynol and trichloroethanol in biological fluids by gas-liquid chromatography as an aid to the diagnosis of acute poisoning.
J Chromatogr. 1978 Jun 11;153(2):473-9. doi: 10.1016/s0021-9673(00)95507-9.
4
[Development of forensic thanatology through the prism of analysis of postmortem protocols collected at the Department of Forensic Medicine, Jagiellonian University].[通过对雅盖隆大学法医学系收集的尸体解剖记录进行分析来探讨法医死亡学的发展]
Arch Med Sadowej Kryminol. 2011 Jul-Sep;61(3):213-300.
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[Skin necrosis due to intake of clomethiazol (distaneurin) in combination with alcohol].[因同时摄入氯美噻唑(二乙硫胺)和酒精导致的皮肤坏死]
Z Hautkr. 1980 Jul 1;55(13):868-70.
6
[Homicidal poisoning by aconite: report of a case from the viewpoint of clinical forensic medicine].[乌头碱中毒杀人案:临床法医学视角的病例报告]
Nihon Hoigaku Zasshi. 1990 Aug;44(4):352-7.
7
Poisoning with chlormethiazole.氯美噻唑中毒
Br Med J. 1979 Nov 10;2(6199):1218-9. doi: 10.1136/bmj.2.6199.1218-c.
8
Clomethiazol tablets induce ulcers in the esophoagus.氯美噻唑片会引发食管溃疡。
Z Gastroenterol. 1982 Sep;20(9):469-73.
9
Toxicological investigations of six chlormethiazole-related deaths.六例与氯美噻唑相关死亡的毒理学调查。
Forensic Sci Int. 1979 Jul-Aug;14(1):49-55. doi: 10.1016/0379-0738(79)90154-3.
10
Driving under the influence of chlormethiazole.在氯美噻唑影响下驾驶。
Forensic Sci Int. 2005 Oct 29;153(2-3):213-7. doi: 10.1016/j.forsciint.2005.05.011.

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Rebound effect, discontinuation, and withdrawal syndromes associated with drugs used in psychiatric and neurological disorders.与精神和神经疾病用药相关的反跳效应、停药反应及戒断综合征。
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本文引用的文献

1
A collection of therapeutic, toxic and fatal blood drug concentrations in man.人体治疗性、中毒性和致死性血药浓度汇编。
Hum Toxicol. 1983 Jul;2(3):437-64. doi: 10.1177/096032718300200301.
2
Hypnotics and sedatives: an index of fatal toxicity.催眠药和镇静药:致命毒性指标
Lancet. 1981 Feb 14;1(8216):387-8. doi: 10.1016/s0140-6736(81)91709-8.
3
[Gas chromatography detection of chlormethiazole].[气相色谱法检测氯美噻唑]
Beitr Gerichtl Med. 1972;29:414-6.
4
Death after taking medicaments.服药后死亡。
Br Med J. 1974 Mar 16;1(5906):501-4. doi: 10.1136/bmj.1.5906.501.
5
Metabolism studies of chlormethiazole by gas chromatography-mass spectrometry.
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Gas chromatographic determination of drugs in post-mortem blood.气相色谱法测定死后血液中的药物
Ann Med Exp Biol Fenn. 1972;50(4):175-9.
7
Chlormethiazole poisoning (a case report).氯美噻唑中毒(病例报告)
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8
Deaths in connection with chlormethiazole (heminevrin) therapy.
Int J Clin Pharmacol Biopharm. 1976 Oct;14(3):225-30.
9
Fatal chlormethiazole poisoning in chronic alcoholics.慢性酒精中毒患者的致命性氯美噻唑中毒
Br Med J. 1977 Sep 3;2(6087):614. doi: 10.1136/bmj.2.6087.614.
10
[Therapeutic concentrations of chlormethiazol in blood and their detection (author's transl)].血液中氯美噻唑的治疗浓度及其检测(作者译)
Z Rechtsmed. 1977 Jul 5;80(1):27-33. doi: 10.1007/BF02332344.