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儿童耳鼻喉恶性肿瘤

Malignant otolaryngological tumors in children.

作者信息

Benoit Y, Delbeke M J, Van Cauwenberge P, Kluyskens P

出版信息

Acta Otorhinolaryngol Belg. 1984;38(3):288-301.

PMID:6516833
Abstract

The details of 37 children presenting a malignant tumor in the ENT-region (period 1950-1983) are presented and discussed. The prevalence was higher in boys than in girls and the most common tumors were non-Hodgkin lymphoma (n = 14) and rhabdomyosarcoma (n = 13). The most common primary sites were the nasopharynx (9 cases), the paranasal sinuses (7 cases) and the soft tissue in the parotid region (7 cases). In 23 children the presence of a painless tumor was the first symptom, in 11 pain was predominant. Only a minority (5 children) presented a limited tumor; in 20 children there was a local extension of the tumor and in 10 children metastases were present at the first visit. The beneficial role of chemotherapy and the necessity of a good teamwork in the treatment of these children is outlined. Of the 37 children, 14, (38%) are surviving; of these 14 children, 12 are off therapy and cured. It is demonstrated that the prognosis improved considerably since the last 14 years.

摘要

本文呈现并讨论了1950年至1983年间37例耳鼻喉区域出现恶性肿瘤的儿童病例详情。男孩的患病率高于女孩,最常见的肿瘤是非霍奇金淋巴瘤(14例)和横纹肌肉瘤(13例)。最常见的原发部位是鼻咽部(9例)、鼻窦(7例)和腮腺区软组织(7例)。23名儿童的首发症状为无痛性肿瘤,11名以疼痛为主。仅有少数(5名儿童)表现为局限性肿瘤;20名儿童肿瘤有局部扩展,10名儿童初诊时即有转移。概述了化疗在治疗这些儿童中的有益作用以及良好团队协作的必要性。37名儿童中,14名(38%)存活;这14名儿童中,12名已停止治疗且治愈。结果表明,与过去14年相比,预后有了显著改善。

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