Kopsa H, Schmidt P, Zazgornik J, Balcke P, Deutsch E
Med Klin. 1978 May 5;73(18):668-70.
A case of multiple myeloma with severe osteolytic destructions and myeloma kidney is presented, in whom a rapidly progressive renal insufficiency because of hyponatraemia and dehydration developed. After 5 months of regular dialysis treatment diuresis increased and a sufficient global kidney function recurred. Aetiological factors and the pathomechanisms of acute renal failure in multiple myeloma are discussed. We assume that acute renal insufficiency is - in rare cases - at least partly reversible. Therefore patients with acute renal failure and multiple myeloma should not be excluded from haemodialysis treatment because even complete rehabilitation can be achieved.
本文报告一例伴有严重溶骨性破坏和骨髓瘤肾病的多发性骨髓瘤患者,该患者因低钠血症和脱水出现快速进展的肾功能不全。经过5个月的规律透析治疗后,尿量增加,整体肾功能恢复良好。文中讨论了多发性骨髓瘤急性肾衰竭的病因及发病机制。我们认为,在罕见情况下,急性肾功能不全至少部分是可逆的。因此,急性肾衰竭的多发性骨髓瘤患者不应被排除在血液透析治疗之外,因为即使是完全康复也是有可能实现的。