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瑞氏综合征中的鸟氨酸氨甲酰基转移酶

Ornithine carbamyl transferase in Reye's syndrome.

作者信息

Deshmukh D R, Remington P L

出版信息

Biochem Med. 1984 Dec;32(3):337-40. doi: 10.1016/0006-2944(84)90039-5.

DOI:10.1016/0006-2944(84)90039-5
PMID:6517878
Abstract

Serum levels of ornithine carbamyl transferase activities were determined in the acutely ill and convalescent Reye's syndrome patients and in their parents. Acutely ill Reye's syndrome patients had elevated levels of serum ornithine carbamyl transferase activities as compared to those in controls. The convalescent Reye's syndrome patients and their parents had normal levels of serum ornithine carbamyl transferase activities. These results suggest that an inborn metabolic defect was not responsible for the increase in serum ornithine carbamyl transferase activities in Reye's syndrome.

摘要

对急性病期和恢复期的瑞氏综合征患者及其父母测定了血清鸟氨酸氨甲酰转移酶活性水平。与对照组相比,急性病期的瑞氏综合征患者血清鸟氨酸氨甲酰转移酶活性水平升高。恢复期的瑞氏综合征患者及其父母血清鸟氨酸氨甲酰转移酶活性水平正常。这些结果表明,先天性代谢缺陷并非瑞氏综合征患者血清鸟氨酸氨甲酰转移酶活性增加的原因。

相似文献

1
Ornithine carbamyl transferase in Reye's syndrome.瑞氏综合征中的鸟氨酸氨甲酰基转移酶
Biochem Med. 1984 Dec;32(3):337-40. doi: 10.1016/0006-2944(84)90039-5.
2
Serum glutamate dehydrogenase and ornithine carbamyl transferase in Reye's syndrome.
Enzyme. 1985;33(3):171-4. doi: 10.1159/000469428.
3
Serum ornithine carbamyl transferase activities in Reye's syndrome.瑞氏综合征中的血清鸟氨酸氨基甲酰转移酶活性
Enzyme. 1982;27(1):45-51. doi: 10.1159/000459021.
4
Transiently reduced activity of carbamyl phosphate synthetase and ornithine transcarbamylase in liver of children with Reye's syndrome.瑞氏综合征患儿肝脏中氨甲酰磷酸合成酶和鸟氨酸转氨甲酰酶的活性短暂降低。
N Engl J Med. 1976 Apr 15;294(16):861-7. doi: 10.1056/NEJM197604152941602.
5
Hepatic polyamine metabolism in children with Reye's syndrome.瑞氏综合征患儿的肝脏多胺代谢
Enzyme. 1991;45(4):209-14. doi: 10.1159/000468891.
6
Masking by enzyme inhibitor of raised serum glutamate dehydrogenase activity in Reye's syndrome.
Lancet. 1983 Jul 2;2(8340):4-7. doi: 10.1016/s0140-6736(83)90002-8.
7
Serum enzyme alterations in arginine-deficient, influenza-infected ferrets: a potential animal model of Reye's syndrome.精氨酸缺乏、感染流感的雪貂血清酶变化:瑞氏综合征的一种潜在动物模型。
Enzyme. 1982;27(1):52-7. doi: 10.1159/000459022.
8
Letter: Carbamyl phosphate synthetase and ornithine transcarbamylase in liver of Reye's syndrome.信件:瑞氏综合征肝脏中的氨甲酰磷酸合成酶和鸟氨酸转氨甲酰酶
N Engl J Med. 1974 Oct 10;291(15):797-8. doi: 10.1056/NEJM197410102911523.
9
Human ornithine transcarbamylase. Purification and characterization of the enzyme from normal liver and the liver of a Reye's syndrome patient.人鸟氨酸转氨甲酰酶。从正常肝脏和瑞氏综合征患者肝脏中纯化并鉴定该酶。
J Biol Chem. 1977 Sep 25;252(18):6464-9.
10
Displacement of hepatic ornithine carbamoyltransferase from mitochondria to cytosol in Reye's syndrome.
Biochem Med Metab Biol. 1991 Oct;46(2):255-62. doi: 10.1016/0885-4505(91)90073-t.

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