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瑞氏综合征中的鸟氨酸氨甲酰基转移酶

Ornithine carbamyl transferase in Reye's syndrome.

作者信息

Deshmukh D R, Remington P L

出版信息

Biochem Med. 1984 Dec;32(3):337-40. doi: 10.1016/0006-2944(84)90039-5.

Abstract

Serum levels of ornithine carbamyl transferase activities were determined in the acutely ill and convalescent Reye's syndrome patients and in their parents. Acutely ill Reye's syndrome patients had elevated levels of serum ornithine carbamyl transferase activities as compared to those in controls. The convalescent Reye's syndrome patients and their parents had normal levels of serum ornithine carbamyl transferase activities. These results suggest that an inborn metabolic defect was not responsible for the increase in serum ornithine carbamyl transferase activities in Reye's syndrome.

摘要

对急性病期和恢复期的瑞氏综合征患者及其父母测定了血清鸟氨酸氨甲酰转移酶活性水平。与对照组相比,急性病期的瑞氏综合征患者血清鸟氨酸氨甲酰转移酶活性水平升高。恢复期的瑞氏综合征患者及其父母血清鸟氨酸氨甲酰转移酶活性水平正常。这些结果表明,先天性代谢缺陷并非瑞氏综合征患者血清鸟氨酸氨甲酰转移酶活性增加的原因。

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