Pavie A, Bors V, Baud F, Gandjbakhch I, Cabrol C
Eur Heart J. 1984 Oct;5 Suppl D:39-42. doi: 10.1093/eurheartj/5.suppl_d.39.
From January 1978 to August 1983, 41 prosthetic valve thromboses in 34 patients were operated upon in our service. They comprised 15 aortic, 25 mitral and one tricuspid valve thromboses. Seven patients had massive thrombus with dysfunction of the prosthesis; others had small and disseminated thrombi on their prosthesis (34 patients). In the aortic position, valve thrombosis occurred on 10 ball valves and 5 pivoting disc valves. In the mitral position, they occurred on 17 ball valves, 7 pivoting disc valves and one bioprosthesis. In 2 cases, aortic valve thrombectomy was successfully done. Others had valve replacement. Hospital mortality was high: 13 deaths. Survivors are free of recurrent valve thrombosis. One had a minor peripheral embolus. Prosthetic valve thrombosis is a serious condition. There are special problems related to diagnosis and treatment of these patients which we discuss, according to our experience of more than 4000 valvular replacements.
1978年1月至1983年8月,我院对34例患者的41例人工瓣膜血栓形成进行了手术治疗。其中包括15例主动脉瓣、25例二尖瓣和1例三尖瓣血栓形成。7例患者有大量血栓伴人工瓣膜功能障碍;其他患者人工瓣膜上有小的和散在的血栓(34例患者)。在主动脉瓣位,瓣膜血栓形成发生于10个球瓣和5个旋转碟瓣。在二尖瓣位,血栓形成发生于17个球瓣、7个旋转碟瓣和1个生物瓣。2例成功进行了主动脉瓣血栓切除术。其他患者进行了瓣膜置换。医院死亡率很高:13例死亡。幸存者无瓣膜血栓复发。1例有轻微的外周栓塞。人工瓣膜血栓形成是一种严重的疾病。根据我们超过4000例瓣膜置换的经验,我们讨论了与这些患者的诊断和治疗相关的特殊问题。