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猪尾状核中儿茶酚胺浓度的年龄和基因型依赖性差异。

Age- and genotype-dependent differences in catecholamine concentrations in the porcine caudate nucleus.

作者信息

Draper D D, Rothschild M F, Beitz D C, Christian L L

出版信息

Exp Gerontol. 1984;19(6):377-81. doi: 10.1016/0531-5565(84)90047-0.

Abstract

Catecholamine concentrations of the caudate nucleus were determined by radioenzymatic assay in stress-susceptible and stress-resistant pigs at five different ages. Dopamine concentrations increased with age up to the time of puberty and declined thereafter in both genotypes of pigs. Generally, epinephrine concentrations increased with increasing age in both genotypes of pigs. Norepinephrine concentrations remained relatively constant for all ages of pigs except the oldest pigs. For most age groups, dopamine concentrations were lower in pigs of stress-susceptible genotype than in stress-resistant genotype.

摘要

通过放射酶分析法测定了五个不同年龄段应激易感猪和应激抗性猪尾状核中的儿茶酚胺浓度。多巴胺浓度在青春期前随年龄增加而升高,此后在两种基因型的猪中均下降。一般来说,两种基因型猪的肾上腺素浓度均随年龄增长而增加。除了最老的猪之外,所有年龄段猪的去甲肾上腺素浓度保持相对恒定。在大多数年龄组中,应激易感基因型猪的多巴胺浓度低于应激抗性基因型猪。

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