Viru A A, Varrik E V, Eépik V E, Pékhme A Ia
Fiziol Zh SSSR Im I M Sechenova. 1984 Dec;70(12):1624-8.
The 20-hr swimming increased the contants of protein, thyrosine and 3-methylhistidine (also per 1 g of protein) in skeletal muscle of rat within 2-24 hrs. A significant increase in 3-methylhistidine excretion followed this on the 2nd day of the recovery period. The revealed combination of changes suggests a simultaneous augmentation of both synthesis and disintegration of protein in muscles after their activity. Hence, the increased excretion of 3-methylhistidine during recovery period reflects an intensive renewal of the molecular content of proteins of actinomyosine complex. The 3-methylhistidine level in intestine increased only for a short time and seems not to contribute to the delayed increase in excretion of the amino acid.
20小时的游泳运动在2至24小时内增加了大鼠骨骼肌中蛋白质、酪氨酸和3-甲基组氨酸(每1克蛋白质中的含量)的含量。在恢复期的第2天,3-甲基组氨酸的排泄量显著增加。所揭示的这些变化表明,肌肉活动后蛋白质的合成和分解同时增强。因此,恢复期3-甲基组氨酸排泄量的增加反映了肌动球蛋白复合物蛋白质分子含量的强烈更新。肠道中3-甲基组氨酸的水平仅在短时间内升高,似乎与该氨基酸排泄的延迟增加无关。