Cheli R, Giacosa A
Hepatogastroenterology. 1984 Dec;31(6):272-3.
Absorption behavior was studied in 6 patients with chronic atrophic duodenitis and compared with that observed in 6 cases of untreated celiac disease. The histobioptic study of the duodenal and jejunal mucosa showed that in atrophic duodenitis the lesions involve just one or two duodenal portions with normal jejunal mucosa: in contrast it was confirmed that in celiac disease atrophic lesions extended from the duodenal to the jejunal mucosa. From the clinical point of view, patients with chronic atrophic duodenitis do not show evidence of malabsorption while such phenomena occur consistently, even though in varied form, in celiac disease. The possible reason for this clinical behavior seems to be linked to the different extention of the histological damage in the two diseases. In conclusion, chronic atrophic atrophic duodenitis is a clinically autonomous entity as compared with gluten enteropathy.
对6例慢性萎缩性十二指肠炎症患者的吸收行为进行了研究，并与6例未经治疗的乳糜泻患者的吸收行为进行了比较。十二指肠和空肠黏膜的组织活检研究表明，在萎缩性十二指肠炎症中，病变仅累及十二指肠的一两个部分，空肠黏膜正常：相比之下，已证实乳糜泻中的萎缩性病变从十二指肠延伸至空肠黏膜。从临床角度来看，慢性萎缩性十二指肠炎症患者没有吸收不良的迹象，而在乳糜泻中，这种现象持续出现，尽管形式多样。这种临床行为的可能原因似乎与两种疾病组织学损伤的不同范围有关。总之，与麸质肠病相比，慢性萎缩性十二指肠炎症是一种临床上独立的疾病实体。
