Moore G S, Calabrese E J, Schulz E
J Environ Pathol Toxicol Oncol. 1984 Jul;5(4-5):71-8.
Female Dorset sheep were exposed in vivo to ambient ozone levels of 0.12 ppm, 0.25 ppm, 0.50 ppm, 0.70 ppm for 2.75 hours and the effects of this exposure upon erythrocytes were studied. Ozone exposure induced biochemical evidence of oxidant stress as indicated by decreases in GSH levels (at 0.5 and 0.7 ppm ozone) and ACHE (at 0.7 ppm), increases in MetHb (from 0.12 ppm upward) and decreases in red blood cell counts (from 0.12 ppm upward). However, only the decrease in GSH levels at the 0.5 ppm ozone exposure was statistically significant (p = 0.05).
将雌性多塞特羊在体内暴露于0.12 ppm、0.25 ppm、0.50 ppm、0.70 ppm的环境臭氧水平下2.75小时，并研究这种暴露对红细胞的影响。臭氧暴露诱导了氧化应激的生化证据，表现为谷胱甘肽水平降低（在0.5 ppm和0.7 ppm臭氧浓度下）和乙酰胆碱酯酶降低（在0.7 ppm下），高铁血红蛋白增加（从0.12 ppm起）以及红细胞计数减少（从0.12 ppm起）。然而，仅在0.5 ppm臭氧暴露下谷胱甘肽水平的降低具有统计学意义（p = 0.05）。
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