Guillard O, Courtois P, Murai P, Ducassou D, Reiss D
J Pharm Sci. 1984 Nov;73(11):1642-3. doi: 10.1002/jps.2600731139.
The pharmacokinetics of zinc sulfate were compared with those of a new zinc salt, pantothenate, in rabbits. Each salt was administered at a dosage of 3.3 microCi of zinc-65/kg of body weight. The measured pharmacokinetics of the two compounds responded to a two-compartment open model. The urinary elimination of the two salts was similar, as was their localization in the skin and fur, but zinc pantothenate was fixed by the liver to a lesser extent than was zinc sulfate.
在兔子身上比较了硫酸锌与一种新的锌盐泛酸盐的药代动力学。每种盐均以3.3微居里的65锌/千克体重的剂量给药。所测得的这两种化合物的药代动力学符合二室开放模型。两种盐的尿排泄情况相似，它们在皮肤和毛发中的定位情况也相似，但泛酸锌在肝脏中的固定程度低于硫酸锌。
