Gokin A P
Neirofiziologiia. 1978;10(2):162-72.
Experiments on anesthetized cats with partial lesions of the spinal cord show that reticulospinal pathways in the ventral part of the lateral funiculus take part in the polysynaptic reflex inhibition caused by stimulation of ipsi- and contralateral reticular formation. The reticulofugal volley in the ventrolateral funiculus produced relatively short (up to 7 ms) inhibitory PSP in some motoneurons of the internal intercostal nerve and at the same time long-lasting depression of EPSPs evoked by high-threshold segmentary afferents. This volley also caused inhibitory PSP in segmental interneurons (in 14 out of 91, i.e. 15.5%). The IPSPs lasted no longer than 100 ms, while the segmentary excitatory responses of 21 out of 43 interneurons were depressed for 120-500 ms. The described inhibitory action of the lateral reticulospinal system on segmentary reflex pathways is suggested to be caused by several synaptic mechanisms which do not necessarily include hyperpolarization of spinal neurons. Possible mechanisms of such inhibition are discussed.
对脊髓部分损伤的麻醉猫进行的实验表明，外侧索腹侧的网状脊髓通路参与了由同侧和对侧网状结构刺激引起的多突触反射抑制。腹外侧索中的网状传出冲动在一些肋间内神经运动神经元中产生相对较短（最长7毫秒）的抑制性突触后电位（PSP），同时使高阈值节段性传入纤维诱发的兴奋性突触后电位（EPSP）产生持久抑制。该冲动还在节段性中间神经元中引起抑制性PSP（91个中有14个，即15.5%）。抑制性突触后电位持续时间不超过100毫秒，而43个中间神经元中有21个的节段性兴奋反应被抑制120 - 500毫秒。外侧网状脊髓系统对节段性反射通路的上述抑制作用被认为是由几种突触机制引起的，这些机制不一定包括脊髓神经元的超极化。文中讨论了这种抑制的可能机制。
