Bulychev V V, Davydovskiĭ V I, Bulycheva I V
Kardiologiia. 1984 Sep;24(9):109-11.
The study has revealed that active forms of infectious endocarditis constitute 30-50% of all septic diseases in hospitals. It is the normal cusps of the valvular apparatus of the left cardiac portion that are predominantly damaged, deformed or destroyed. Endocardial involvement of the right portion of the heart and the pulmonary artery occurs very rarely. Infectious patients develop sepsis more frequently than patients with non-infectious diseases but it takes the form of acute infectious endocarditis less commonly. Currently the clinical course of acute infectious endocarditis is characterized by predominantly ulcerous thrombotic damage of the normal valves with the formation of heart disease, the development of congestive insufficiency of the circulation and thromboembolic complications and the lethal outcome in the first weeks of hospitalization in 95.6% of patients with acute endocarditis in infectious and 56.6% in non-infectious hospitals.
该研究表明,活动性感染性心内膜炎在医院所有败血症性疾病中占30%-50%。主要受损、变形或破坏的是左心部分瓣膜装置的正常瓣叶。心脏右侧及肺动脉的心内膜受累极为罕见。感染性疾病患者比非感染性疾病患者更易发生败血症,但急性感染性心内膜炎的形式较少见。目前,急性感染性心内膜炎的临床病程主要表现为正常瓣膜的溃疡性血栓形成损害,并伴有心脏病的形成、循环充血性功能不全和血栓栓塞并发症,在感染性医院95.6%的急性感染性心内膜炎患者以及非感染性医院56.6%的患者中,会在住院的头几周出现致命结局。