Bobkova V I, Lokshina L I, Sidakova M M, Tananova G V, Fomchenkov S I
Kardiologiia. 1984 Sep;24(9):54-7.
Hypolipidemic therapy should be developed as a therapy aimed at the normalization of metabolism since the functional relationship of lipid and carbohydrate metabolism is evident both in normal and pathological conditions. The results of the reaction of the lipid spectrum of the blood to a single glucose load confirms that patients with combined hyperlipoproteinemias (IIb type) are heterogeneous in terms of the pathogenesis of the metabolic disturbances which should be taken into account in assessing the efficiency of hypolipidemic drugs as well as in selecting and administering medicines.
由于脂质和碳水化合物代谢的功能关系在正常和病理状态下都很明显,降血脂治疗应发展成为一种旨在使代谢正常化的疗法。血液脂质谱对单次葡萄糖负荷反应的结果证实,合并高脂蛋白血症(IIb型)患者在代谢紊乱的发病机制方面存在异质性,这在评估降血脂药物的疗效以及选择和使用药物时都应予以考虑。