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1965年至1982年期间,布拉格大学医院儿科肿瘤诊所对儿童神经母细胞瘤的治疗。

Treatment of childhood neuroblastoma at the Clinic of Pediatric Oncology of the Faculty Hospital in Prague during 1965-1982.

作者信息

Smelhaus V, Koutecký J, Abrahámová J

出版信息

Neoplasma. 1984;31(6):709-17.

PMID:6521798
Abstract

The results of a complex treatment of 93 patients with neuroblastoma treated at the Clinic of Pediatric Oncology in Prague during the period of 1965-1982 are presented. A group of 41 patients treated during 1965-1977 was compared to that of 52 patients treated during 1978-1982. The latter group received a more intense chemotherapy treatment. In Group A there survived 7 patients (16.28%), all of them without symptoms of neuroblastoma. In Group B did so 31 patients (59.61%), 25 of them (48.08%) without symptoms of the disease, however, the results obtained in this group are of rather recent origin. A comparison made by means of the log-rank test and by extrapolating the data from curves of survival rates revealed no statistically significant improvement.

摘要

本文呈现了1965年至1982年期间在布拉格儿科肿瘤诊所接受治疗的93例神经母细胞瘤患者的综合治疗结果。将1965年至1977年期间接受治疗的41例患者与1978年至1982年期间接受治疗的52例患者进行了比较。后一组接受了更强化的化疗。A组有7例患者存活(16.28%),所有患者均无神经母细胞瘤症状。B组有31例患者存活(59.61%),其中25例(48.08%)无疾病症状,然而,该组获得的结果是近期的。通过对数秩检验以及从生存率曲线外推数据进行的比较显示,没有统计学上的显著改善。

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