大鼠梨状前皮质而非犰狳梨状前皮质中诱发的晚期成分的起源和可塑性特性。

Origin and plastic properties of late components evoked in the rat's but not in the armadillo's prepyriform cortex.

作者信息

Ferreyra Moyano H, Cinelli A R, Molina J C

出版信息

Neurosci Lett. 1984 Dec 21;52(3):305-10. doi: 10.1016/0304-3940(84)90179-4.

PMID:6521973

Abstract

Following ipsilateral olfactory bulb (IOB) stimulation long-latency (62-89 ms) gross and unit responses were evoked in the prepyriform cortex of rats prepared under urethane or pentobarbital, but were absent in 23 armadillos explored under the same anesthetics. Depth profile and current source density analysis revealed that generators of early and late components (LC) lie within cortical layers Ia-Ib, suggesting that LC may represent a compound depolarizing excitatory postsynaptic potential, generated by recurrent excitation of pyramidal cells. LC satisfied, in addition, several parametric requirements for habituation, favoring the hypothesis that late response waning following a period of predictable, repetitive and invariant stimulation, might be related to behavioral habituation to odors.

摘要

在对同侧嗅球（IOB）进行刺激后，在经乌拉坦或戊巴比妥麻醉的大鼠梨状前皮质中诱发了长潜伏期（62 - 89毫秒）的总体反应和单位反应，但在相同麻醉条件下探索的23只犰狳中未观察到此类反应。深度剖面图和电流源密度分析表明，早期和晚期成分（LC）的发生器位于皮质层Ia - Ib内，这表明LC可能代表由锥体细胞的反复兴奋产生的复合去极化兴奋性突触后电位。此外，LC满足了习惯化的几个参数要求，这支持了以下假设：在一段可预测、重复且不变的刺激后晚期反应减弱，可能与对气味的行为习惯化有关。