在黑人中产生的抗Fy3的三个例子。

Three examples of anti-Fy3 produced in Negroes.

作者信息

Kosinski K S, Molthan L, White L

出版信息

Rev Fr Transfus Immunohematol. 1984 Oct;27(5):619-24. doi: 10.1016/s0338-4535(84)80083-5.

Abstract

We present three examples of anti-Fy3 produced by Negroes. Results of serologic studies were similar to those of previously reported examples of Negro produced anti-Fy3, including negative to weak reactivity with cord red blood cells, separable anti-Fya, and the presence of multiple unexpected alloantibodies. These findings reinforce the difference between anti-Fy3 produced by Negroes and that produced by non-Negroes. The rare formation of Duffy antibodies by Negroes may signify the presence of an amorphic gene at the Duffy locus.

摘要

我们展示了由黑人产生的抗Fy3的三个例子。血清学研究结果与先前报道的黑人产生的抗Fy3的例子相似，包括与脐血红细胞反应阴性至弱阳性、可分离的抗Fya以及存在多种意外的同种抗体。这些发现强化了黑人产生的抗Fy3与非黑人产生的抗Fy3之间的差异。黑人中罕见的达菲抗体形成可能表明达菲基因座存在无效基因。