Wang D B, Wang X C
Sci Sin B. 1984 Sep;27(9):905-9.
The biological characteristics of mouse macrophage-like cell line (MMC-1) are described. This cell line has been cultured in vitro for more than 20 months. MMC-1 cells are adherent to typical morphology of macrophages, but bigger in size than those of the uncultivated. They are actively phagocytic with abundant Fc receptors. The karyotypes are mostly pantaploidy. This cell line provides a useful tool for the biological and immunological study of macrophage.
描述了小鼠巨噬细胞样细胞系(MMC-1)的生物学特性。该细胞系已在体外培养20多个月。MMC-1细胞具有典型巨噬细胞的形态且贴壁生长,但其大小比未培养的巨噬细胞大。它们具有活跃的吞噬作用且有丰富的Fc受体。其核型大多为多倍体。该细胞系为巨噬细胞的生物学和免疫学研究提供了一个有用的工具。