Tavasolian B, Kharrazy P
Pahlavi Med J. 1978 Jan;9(1):21-6.
Ricinus communis L., usually cultivated for production of oil, has some use in medicine, cosmetic industries and as motor oil. The defatted seed meal is very toxic, and can not be used as human or animal food. This study undertook extraction and identification of ricin, a toxalbumine, from Iranian Ricinus communis L. Ricin, was extracted from the seeds using dilute acid solution, salted out with ammonium sulfate, and purified by Sephadex G - 75 and DEAE - cellulose column chromatography. Disc electrophoresis showed the degree of the purification. Ricin is an anti-tumor and allergenic compound. It is also useful in biochemical research in gene control and protein systhesis.
蓖麻，通常种植用于生产油脂，在医药、化妆品工业以及作为机油方面有一些用途。脱脂籽粕毒性很强，不能用作人类或动物的食物。本研究对从伊朗蓖麻中提取和鉴定毒蛋白蓖麻毒素进行了研究。蓖麻毒素是从种子中用稀酸溶液提取的，用硫酸铵盐析，然后通过葡聚糖凝胶G - 75和二乙氨基乙基纤维素柱色谱法进行纯化。圆盘电泳显示了纯化程度。蓖麻毒素是一种抗肿瘤和致敏化合物。它在基因控制和蛋白质合成的生化研究中也很有用。
