[硫唑嘌呤及其副作用]
[Azathioprine and its side effects].
作者信息
Montag H
出版信息
Z Hautkr. 1984 Dec 1;59(23):1600-7.
PMID:6523959
Abstract
The clinical signs and symptoms of a patient induced us to consider critically the so far known side effects of azathioprine. The literature concerning 643 patients treated with azathioprine reports on reactions as changes in blood count, gastro-intestinal complaints, intrahepatic cholestasis, acute pancreatitis, and leukemia. Irreversible side effects occurred in four cases.
摘要
一位患者的临床症状和体征促使我们审慎考虑硫唑嘌呤目前已知的副作用。有关643例接受硫唑嘌呤治疗患者的文献报道了诸如血细胞计数变化、胃肠道不适、肝内胆汁淤积、急性胰腺炎和白血病等反应。4例出现了不可逆的副作用。
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